Trokendi Xr Drug Interactions: 99 Major, 437 Moderate
Trokendi Xr (Topiramate) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Trokendi Xr. Always confirm against the full prescribing information.
100 interactions
Abrocitinib
The metabolism of Abrocitinib can be decreased when combined with Topiramate.
Level 2 evidence
Acetazolamide
The risk or severity of adverse effects can be increased when Topiramate is combined with Acetazolamide.
Level 1 evidence
Aclidinium
The risk or severity of hyperthermia and oligohydrosis can be increased when Aclidinium is combined with Topiramate.
Level 1 evidence
Aficamten
The metabolism of Aficamten can be decreased when combined with Topiramate.
Level 2 evidence
Albendazole
The metabolism of Albendazole can be increased when combined with Topiramate.
Level 2 evidence
Alfentanil
The risk or severity of CNS depression can be increased when Topiramate is combined with Alfentanil.
Level 2 evidence
Almotriptan
The risk or severity of CNS depression can be increased when Topiramate is combined with Almotriptan.
Level 2 evidence
Alosetron
The risk or severity of CNS depression can be increased when Topiramate is combined with Alosetron.
Level 2 evidence
Alprazolam
The risk or severity of CNS depression can be increased when Topiramate is combined with Alprazolam.
Level 2 evidence
Amikacin
Topiramate may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Amisulpride
The risk or severity of CNS depression can be increased when Topiramate is combined with Amisulpride.
Level 2 evidence
Amitriptyline
The risk or severity of hyperthermia and oligohydrosis can be increased when Amitriptyline is combined with Topiramate.
Level 1 evidence
Enter your NPI to unlock 9 major interactions for Trokendi Xr
Trokendi Xr (Topiramate) has 1044 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Trokendi Xr (Topiramate) has 99 major, 437 moderate, and 508 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Trokendi Xr. Always confirm against the full prescribing information.