Voraxaze (Glucarpidase) Drug Interactions: 5 Moderate
Voraxaze (Glucarpidase) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Voraxaze. Always confirm against the full prescribing information.
9 interactions
5-methyltetrahydrofolic acid
The serum concentration of the active metabolites of 5-methyltetrahydrofolic acid can be reduced when 5-methyltetrahydrofolic acid is used in combination with Glucarpidase resulting in a loss in efficacy.
Level 1 evidence
Folic acid
The serum concentration of the active metabolites of Folic acid can be reduced when Folic acid is used in combination with Glucarpidase resulting in a loss in efficacy.
Level 1 evidence
Leucovorin
The serum concentration of the active metabolites of Leucovorin can be reduced when Leucovorin is used in combination with Glucarpidase resulting in a loss in efficacy.
Level 1 evidence
Levoleucovorin
The serum concentration of the active metabolites of Levoleucovorin can be reduced when Levoleucovorin is used in combination with Glucarpidase resulting in a loss in efficacy.
Level 1 evidence
Levomefolic acid
The serum concentration of the active metabolites of Levomefolic acid can be reduced when Levomefolic acid is used in combination with Glucarpidase resulting in a loss in efficacy.
Level 1 evidence
Methotrexate
The serum concentration of the active metabolites of Methotrexate can be reduced when Methotrexate is used in combination with Glucarpidase resulting in a loss in efficacy.
Level 1 evidence
Pafolacianine
The serum concentration of the active metabolites of Pafolacianine can be reduced when Pafolacianine is used in combination with Glucarpidase resulting in a loss in efficacy.
Level 1 evidence
Pemetrexed
The serum concentration of the active metabolites of Pemetrexed can be reduced when Pemetrexed is used in combination with Glucarpidase resulting in a loss in efficacy.
Level 1 evidence
Pralatrexate
The serum concentration of the active metabolites of Pralatrexate can be reduced when Pralatrexate is used in combination with Glucarpidase resulting in a loss in efficacy.
Voraxaze (Glucarpidase) has 9 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Voraxaze (Glucarpidase) has 0 major, 5 moderate, and 4 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Voraxaze. Always confirm against the full prescribing information.