Calcitonin Gene-related Peptide Antagonist

Calcitonin Gene-related Peptide Antagonists

<section class="Section" data-sectioncode="34089-3"><a name="LINK_7ed0975d-d0c2-465e-aeef-d5e55e935595"></a><a name="section-8"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Eptinezumab-jjmr is a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for calcitonin gene-related peptide (CGRP) ligand. Eptinezumab-jjmr has an approximate molecular weight of 143 kD. Eptinezumab-jjmr is produced in <span class="Italics">Pichia pastoris</span> yeast cells by recombinant DNA technology. </p><p>VYEPTI (eptinezumab-jjmr) injection is a sterile, preservative-free, clear to slightly opalescent, colorless to brownish-yellow solution, for intravenous infusion. VYEPTI is supplied as a 100 mg/mL single-dose vial. Each mL contains 100 mg eptinezumab-jjmr formulated in L-histidine (1 mg), L-histidine hydrochloride monohydrate (2.8 mg), polysorbate 80 (0.15 mg), sorbitol (40.5 mg), and Water for Injection, USP, at a pH of 5.8.</p></section>

Vyepti

eptinezumab

eptinezumab-jjmr

1 ML eptinezumab-jjmr 100 MG/ML Injection

1 ML eptinezumab-jjmr 100 MG/ML Injection [Vyepti]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Vypeti is a prescription medication used for migraine prevention. It is administered as an intravenous infusion four times a year. The most common reported side effects were stuffy nose and scratchy throat. 

Vyepti is FDA approved for the following indications: Migraine prevention. 


Report Adverse Event

Prescribing Information

Medication Guide 

Submit MSL Request

Reimbursement Information 

Billing and Coding Guide

Coverage Authorization Request 

Vyepti Connect Enrollment Form

Enroll in Patient Savings Program

Vyepti Infusion Locator 

Other HCP Resources: Access

Other HCP Resources 

About Vyepti

Side Effects 

What to Expect During Treatment

Patient Stories 

Patient Resources 

Nurse Support 

FAQs: Migraine

Instructions For Use (Home Infusion): Migraine 

Patient Brochure 

Doctor Discussion Guide 