Neonatal Fc Receptor Blocker

Neonatal Fc Receptor Blockers

Myasthenia Gravis

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-9"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Efgartigimod alfa-fcab is a human immunoglobulin G1 (IgG1) -derived Fc fragment (fragment, crystallized) of the za allotype. The efgartigimod alfa-fcab Fc fragment is a homodimer consisting of two identical peptide chains each consisting of 227 amino acids linked together by two interchain disulfide bonds with affinity for FcRn. The molecular weight of efgartigimod alfa-fcab is approximately 54 kDa.</p><p>VYVGART (efgartigimod alfa-fcab) injection is a sterile, preservative free, clear to slightly opalescent, colorless to slightly yellow solution supplied in a single-dose vial for infusion after dilution.</p><p>Each 20 mL single-dose vial contains 400 mg of efgartigimod alfa-fcab at a concentration of 20 mg/mL. In addition, each mL of solution contains:</p><dl><dt>-</dt><dd>L-arginine hydrochloride (31.6 mg), polysorbate 80 (0.2 mg), sodium chloride (5.8 mg), sodium phosphate dibasic anhydrous (2.4 mg), sodium phosphate monobasic monohydrate (1.1 mg) and water for injection, USP, at a pH of 6.7 or,</dd><dt>-</dt><dd>L-arginine hydrochloride (10.5 mg), L-histidine (1.4 mg), L- histidine hydrochloride monohydrate (2.2 mg), L-methionine (1.5 mg), polysorbate 80 (0.4 mg), sodium chloride (4.1 mg), sucrose (20.5 mg), and water for injection, USP, at a pH of 6.0.</dd></dl></section>

VYVGART

efgartigimod alfa

efgartigimod alfa-fcab

20 ML efgartigimod alfa-fcab 20 MG/ML Injection

Vyvgart

20 ML efgartigimod alfa-fcab 20 MG/ML Injection [Vyvgart]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information 

Submit MSL Request

Pharmacy List 

Billing & Coding Guide 

How To Order Vygart

Coverage Authorization Request 

Coverage Authorization Appeals 

Letter of Medical Necessity

PA Checklist 

Infusion Center Locator 

My Vyvgart Path Enrollment Form 

My Vyvgart Path Enrollment Form - Online Form 

Enroll in Patient Savings Program 

Other HCP Resources

About Vyvgart 

Receiving Vyvgart 

My Vyvgart Path Support Program 

FAQs: anti-AChR Atibody Positive Generalized Myasthenia Gravis (gMG)

Patient Resources 

Instructions For Use: anti-AChR Atibody Positive Generalized Myasthenia Gravis (gMG)

Patient Brochure

Doctor Discussion Guide 

Myasthenia Gravis Activities of Daily Living (MG-ADL) Scale

Infusion Guide 