Zepbound (Tirzepatide) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Zepbound. Always confirm against the full prescribing information.
100 interactions
Acarbose
The risk or severity of hypoglycemia can be increased when Acarbose is combined with Tirzepatide.Level 2 evidence
Acebutolol
The therapeutic efficacy of Tirzepatide can be increased when used in combination with Acebutolol.Level 1 evidence
Acetylsalicylic acid
The risk or severity of hypoglycemia can be increased when Acetylsalicylic acid is combined with Tirzepatide.Level 1 evidence
Alclometasone
The risk or severity of hyperglycemia can be increased when Alclometasone is combined with Tirzepatide.Level 1 evidence
Alogliptin
The risk or severity of hypoglycemia can be increased when Alogliptin is combined with Tirzepatide.Level 2 evidence
Amcinonide
The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Tirzepatide.Level 1 evidence
Aminosalicylic acid
Aminosalicylic acid may increase the hypoglycemic activities of Tirzepatide.Level 2 evidence
Amiodarone
The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Tirzepatide.Level 2 evidence
Amitriptyline
Amitriptyline may decrease the hypoglycemic activities of Tirzepatide.Level 2 evidence
Amlodipine
The risk or severity of hypoglycemia can be increased when Amlodipine is combined with Tirzepatide.Level 2 evidence
Amoxapine
Amoxapine may decrease the hypoglycemic activities of Tirzepatide.Level 2 evidence
Aripiprazole
The therapeutic efficacy of Tirzepatide can be decreased when used in combination with Aripiprazole.Level 2 evidence
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