What is the dosage of Zytiga?

Zytiga is available in 2 dosages, including 250 mg Tab and 500 mg Tab

What does Zytiga treat?

Zytiga treats Castration-Resistant Prostatic Neoplasms

What is Zytiga made of?

Zytiga contains abiraterone which is a Cytochrome P450 17A1 Inhibitor

How is Zytiga administered?

Zytiga is administered as a Oral Pill

What is Zytiga mechanism of action?

Zytiga mechanism of action is Cytochrome P450 17A1 Inhibitors, Cytochrome P450 2C8 Inhibitors or Cytochrome P450 2D6 Inhibitors

Dosage & Administration Drug label Samples Prior authorization Financial assistance

Patient education

Zytiga

(abiraterone)

abiraterone acetate 250 MG Oral Tablet [Zytiga]abiraterone acetate 500 MG Oral Tablet [Zytiga]

NO BLACK BOX WARNING

Dosage & administration

Metastatic castration-resistant prostate cancer:

* ZYTIGA 1,000 mg orally once daily with prednisone 5 mg orally twice daily.

Metastatic castration-sensitive prostate cancer:

* ZYTIGA 1,000 mg orally once daily with prednisone 5 mg orally once daily.

Patients receiving ZYTIGA should also receive a gonadotropin-releasing hormone (GnRH) analog concurrently or should have had bilateral orchiectomy. ZYTIGA tablets must be taken as a single dose once daily on an empty stomach. Do not eat food 2 hours before and 1 hour after taking ZYTIGA. The tablets must be swallowed whole with water. Do not crush or chew tablets.

Dose Modification:

* For patients with baseline moderate hepatic impairment (Child-Pugh Class B), reduce the ZYTIGA starting dose to 250 mg once daily.
* For patients who develop hepatotoxicity during treatment, hold ZYTIGA until recovery. Retreatment may be initiated at a reduced dose. ZYTIGA should be discontinued if patients develop severe hepatotoxicity.

drug label

Zytiga prescribing information

Have more Zytiga questions?

Submit MSL Request

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Need to report a Zytiga issue?

ONLINE FORMReport adverse event

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samples

Request Zytiga samples

NOT PROVIDED BY BRANDView Online Sample Form

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prior authorization

Zytiga Prior authorization resources

Complete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

NOT PROVIDED BY BRANDCoverage Authorization Appeals

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Benefits investigation

Zytiga Prescription & Pharmacy Benefits Investigation Form

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Reimbursement help (FRM)

NOT PROVIDED BY BRANDReimbursement help (FRM) resources

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financial assistance

Zytiga Financial assistance options

Co-pay savings program

commercial only

Zytiga Prescription & Pharmacy Benefits Investigation Form

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

J&J Patient Assistance Program - Eligibility Check

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Zytiga Patient education