| Acne Vulgaris
Arazlo vs Clindagel
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Arazlo vs Clindagel with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsClindagel has a higher rate of injection site reactions vs Arazlo based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Clindagel but not Arazlo, including UnitedHealthcare
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Category
Arazlo
Clindagel
At A Glance
Topical
Daily
Retinoid
Topical
Once daily
Topical antibiotic (lincosamide)
Indications
- Acne Vulgaris
- Acne Vulgaris
Dosing
Acne Vulgaris Apply a thin layer to affected areas once daily; avoid eyes, mouth, paranasal creases, and mucous membranes; not for oral, ophthalmic, or intravaginal use.
Acne Vulgaris Apply a thin film once daily to the skin where acne lesions appear, covering the entire affected area lightly.
Contraindications
- Pregnancy (may cause fetal harm)
- History of hypersensitivity to preparations containing clindamycin or lincomycin
- History of regional enteritis or ulcerative colitis
- History of antibiotic-associated colitis
Adverse Reactions
Most common (>=1%) Application site pain, application site dryness, application site exfoliation, application site erythema, application site pruritus
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Most common (>=1%) Pruritus, peeling
Serious Severe colitis, pseudomembranous colitis, diarrhea, bloody diarrhea, abdominal pain, gram-negative folliculitis
Pharmacology
Tazarotene is a retinoid prodrug converted by deesterification to tazarotenic acid, which binds to retinoic acid receptors RARalpha, RARbeta, and RARgamma with relative selectivity for RARbeta and RARgamma, potentially modifying gene expression.
Clindamycin phosphate is a semi-synthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, suppressing Propionibacterium acnes growth.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Arazlo
- Covered on 5 commercial plans
- PA (6/12) · Step Therapy (10/12) · Qty limit (9/12)
Clindagel
- Covered on 5 commercial plans
- PA (1/12) · Step Therapy (0/12) · Qty limit (9/12)
UnitedHealthcare
Arazlo
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Clindagel
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (7/8)
Humana
Arazlo
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (0/3)
Clindagel
- Covered on 0 commercial plans
- PA (2/3) · Step Therapy (0/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Arazlo.
No savings programs available for Clindagel.
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ArazloView full Arazlo profile
ClindagelView full Clindagel profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.