| Asthma

Advair HFA vs Qvar RediHaler

Side-by-side clinical, coverage, and cost comparison for asthma.
Deep comparison between: Advair Hfa vs Qvar Redihaler with Prescriber.AI
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Safety signalsQvar Redihaler has a higher rate of injection site reactions vs Advair Hfa based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Qvar Redihaler but not Advair Hfa, including UnitedHealthcare
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Advair Hfa
Qvar Redihaler
At A Glance
Oral inhalation
Twice daily
ICS/LABA combination
Oral inhalation
Twice daily
Inhaled corticosteroid
Indications
  • Asthma
  • Asthma
Dosing
Asthma 2 oral inhalations (45 mcg/21 mcg, 115 mcg/21 mcg, or 230 mcg/21 mcg) twice daily approximately 12 hours apart; starting strength based on asthma severity; maximum 2 inhalations of 230 mcg/21 mcg twice daily.
Asthma (adults and adolescents, >=12 years) 40 to 320 mcg twice daily by oral inhalation, approximately 12 hours apart; starting dose 40 to 80 mcg twice daily for those not on an inhaled corticosteroid; maximum 320 mcg twice daily.
Asthma (pediatric, 4 to 11 years) 40 mcg twice daily by oral inhalation, approximately 12 hours apart; may increase to 80 mcg twice daily after 2 weeks if needed; maximum 80 mcg twice daily.
Contraindications
  • Primary treatment of status asthmaticus or other acute episodes of asthma where intensive measures are required
  • Hypersensitivity to any ingredient of ADVAIR HFA
  • Primary treatment of status asthmaticus or other acute asthma episodes requiring intensive measures
  • Known hypersensitivity to beclomethasone dipropionate or any ingredient in QVAR REDIHALER
Adverse Reactions
Most common (>=3%) Upper respiratory tract infection, throat irritation, headache, nausea and vomiting, musculoskeletal pain, upper respiratory inflammation, viral respiratory infection, hoarseness/dysphonia, dizziness, viral gastrointestinal infection, gastrointestinal signs and symptoms, muscle pain
Serious Serious asthma-related events (hospitalizations, intubations, death), oropharyngeal candidiasis, pneumonia in COPD patients, immunosuppression and risk of infections, hypercorticism and adrenal suppression, cardiovascular and CNS effects, reduction in bone mineral density, growth effects, glaucoma and cataracts
Postmarketing Arrhythmias, hypertension, ventricular tachycardia, Cushing's syndrome, osteoporosis, cataracts, glaucoma, anaphylaxis, esophageal candidiasis, paradoxical bronchospasm, agitation, depression
Most common (>=3%) oral candidiasis, upper respiratory tract infection, nasopharyngitis, oropharyngeal pain, viral upper respiratory tract infection, sinusitis, pharyngitis, headache, pyrexia
Serious oropharyngeal candidiasis, immunosuppression and risk of infections, hypercorticism and adrenal suppression, reduction in bone mineral density, growth effects, glaucoma and cataracts
Postmarketing localized Candida infections, aggression, depression, sleep disorders, psychomotor hyperactivity, suicidal ideation (primarily in children), blurred vision, central serous chorioretinopathy
Pharmacology
ADVAIR HFA combines fluticasone propionate, a synthetic trifluorinated corticosteroid with broad anti-inflammatory activity via glucocorticoid receptor binding, and salmeterol, a selective long-acting beta2-adrenoceptor agonist (LABA) that relaxes bronchial smooth muscle by stimulating adenyl cyclase to increase cyclic AMP levels.
Inhaled corticosteroid prodrug; beclomethasone dipropionate is rapidly hydrolyzed to the active monoester 17-monopropionate (17-BMP), which inhibits inflammatory cells (mast cells, eosinophils, basophils, lymphocytes, macrophages, neutrophils) and release of inflammatory mediators (histamine, eicosanoids, leukotrienes, cytokines) to reduce airway inflammation in asthma.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Advair Hfa
  • Covered on 5 commercial plans
  • PA (9/12) · Step Therapy (5/12) · Qty limit (12/12)
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Qvar Redihaler
  • Covered on 5 commercial plans
  • PA (3/12) · Step Therapy (0/12) · Qty limit (9/12)
View full coverage details ›
UnitedHealthcare
Advair Hfa
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (1/8) · Qty limit (5/8)
View full coverage details ›
Qvar Redihaler
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (0/8) · Qty limit (8/8)
View full coverage details ›
Humana
Advair Hfa
  • Covered on 0 commercial plans
  • PA (0/3) · Step Therapy (0/3) · Qty limit (3/3)
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Qvar Redihaler
  • Covered on 0 commercial plans
  • PA (1/3) · Step Therapy (3/3) · Qty limit (2/3)
View full coverage details ›
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Advair Hfa.
No savings programs available for Qvar Redihaler.
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Advair HfaView full Advair Hfa profile
Qvar RedihalerView full Qvar Redihaler profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.