| Diabetes Mellitus
Admelog vs Apidra
Side-by-side clinical, coverage, and cost comparison for diabetes mellitus.Deep comparison between: Admelog vs Apidra with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsApidra has a higher rate of injection site reactions vs Admelog based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Apidra but not Admelog, including UnitedHealthcare
Sign up to reveal the full AI analysis
Category
Admelog
Apidra
At A Glance
Subcutaneous, Continuous subcutaneous infusion (pump), Intravenous
Within 15 minutes before or immediately after meals
Rapid-acting insulin analog
SC injection
With meals
Rapid-acting insulin analog
Indications
- Diabetes Mellitus
- Diabetes Mellitus
Dosing
Diabetes Mellitus Individualize dose based on route of administration, metabolic needs, blood glucose monitoring, and glycemic control goal. Subcutaneous injection: Administer within 15 minutes before or immediately after a meal into abdominal wall, thigh, upper arm, or buttocks. Continuous subcutaneous infusion (insulin pump): Administer via pump in accordance with pump instructions; change reservoir at least every 7 days. Intravenous infusion: Administer only after dilution (0.1-1 unit/mL in 0.9% Sodium Chloride) under medical supervision. Rotate injection/infusion sites to reduce lipodystrophy risk.
Diabetes Mellitus Inject SC within 15 minutes before a meal or within 20 minutes after starting a meal into the abdomen, thigh, or upper arm; generally use with an intermediate or long-acting insulin.
Continuous Subcutaneous Infusion (Insulin Pump) Administer by CSII using an insulin pump per manufacturer instructions; change reservoir at least every 48 hours; do not dilute or mix with other insulins in the pump.
Intravenous Administration Administer only under medical supervision; dilute to 0.05-1 unit/mL in 0.9% sodium chloride injection using polyvinyl chloride infusion bags.
Contraindications
- Episodes of hypoglycemia
- Hypersensitivity to insulin lispro or any excipient in ADMELOG
- During episodes of hypoglycemia
- Known hypersensitivity to insulin glulisine or any of the excipients in APIDRA
Adverse Reactions
Most common (>=5%) Nasopharyngitis (13%), upper respiratory tract infection (6%).
Severe hypoglycemia 13.5% in type 1 diabetes (52 weeks), 2.4% in type 2 diabetes (26 weeks).
Postmarketing Medication errors with accidental insulin substitution, localized cutaneous amyloidosis at injection site.
Most common (>=5%) Nasopharyngitis, hypoglycemia, upper respiratory tract infection, influenza, peripheral edema, arthralgia, headache
Serious Severe hypoglycemia, anaphylaxis and generalized allergic reactions, hypokalemia, lipodystrophy, worsening of diabetic retinopathy, acute painful peripheral neuropathy
Postmarketing Medication errors with long-acting insulins, localized cutaneous amyloidosis, hyperglycemia and hypoglycemia associated with injection into amyloidosis sites
Pharmacology
Insulin lispro is a rapid-acting insulin analog that regulates glucose metabolism by stimulating peripheral glucose uptake by skeletal muscle and fat, inhibiting hepatic glucose production, inhibiting lipolysis and proteolysis, and enhancing protein synthesis.
Rapid-acting human insulin analog; lowers blood glucose by stimulating peripheral glucose uptake in skeletal muscle and fat and inhibiting hepatic glucose production, with more rapid onset and shorter duration of activity than regular human insulin when given subcutaneously.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Admelog
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (9/12) · Qty limit (9/12)
Apidra
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
UnitedHealthcare
Admelog
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (1/8) · Qty limit (0/8)
Apidra
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (1/8) · Qty limit (0/8)
Humana
Admelog
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (3/3) · Qty limit (0/3)
Apidra
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (3/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Admelog.
No savings programs available for Apidra.
Compare Other Drugs
Let us handle your prior authsJust enter your patient's info and we'll:
- Verify eligibility with the payer.
- Pull the right PA forms directly from the payer.
- Submit, track & send live updates to your dashboard.
Free to start · HIPAA compliant
Next Steps for Your Patient
AdmelogView full Admelog profile
ApidraView full Apidra profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.