| Dry Eye Syndromes
Eysuvis vs Miebo
Side-by-side clinical, coverage, and cost comparison for dry eye syndromes.Deep comparison between: Eysuvis vs Miebo with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsMiebo has a higher rate of injection site reactions vs Eysuvis based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Miebo but not Eysuvis, including UnitedHealthcare
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Category
Eysuvis
Miebo
At A Glance
Ophthalmic
Four times daily
Corticosteroid
Topical (ophthalmic)
4 times daily
Semifluorinated alkane
Indications
- Dry Eye Syndromes
- Dry Eye Syndromes
Dosing
Dry Eye Syndromes Instill one to two drops into each eye four times daily for up to two weeks.
Dry Eye Syndromes Instill one drop four times daily into each affected eye; remove contact lenses prior to and for at least 30 minutes after administration.
Contraindications
- Most viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella
- Mycobacterial infection of the eye
- Fungal diseases of ocular structures
- History of hypersensitivity reaction to perfluorohexyloctane
Adverse Reactions
Most common (>=5%) Instillation site pain
Serious Elevated intraocular pressure, optic nerve damage, visual acuity and field defects, posterior subcapsular cataract formation, delayed wound healing, secondary ocular infection from pathogens including herpes simplex, perforation of the globe
Most common (<4%) blurred vision, conjunctival redness
Premarketing studies hypersensitivity
Pharmacology
Corticosteroid that inhibits the inflammatory response by suppressing edema, fibrin deposition, capillary dilation, leukocyte migration, fibroblast proliferation, and collagen deposition, likely via inhibition of prostaglandin production through glucocorticoid receptor binding.
Perfluorohexyloctane, a semifluorinated alkane, forms a monolayer at the air-liquid interface of the tear film that may reduce evaporation; the exact mechanism of action in dry eye disease is not known.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Eysuvis
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (1/12) · Qty limit (10/12)
Miebo
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (11/12)
UnitedHealthcare
Eysuvis
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (2/8)
Miebo
- Covered on 4 commercial plans
- PA (4/8) · Step Therapy (0/8) · Qty limit (6/8)
Humana
Eysuvis
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (1/3) · Qty limit (2/3)
Miebo
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (3/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Eysuvis.
Cost estimate not availableAssistance Fund: Thyroid Eye Disease (TED)
Commercial or private insurance
Medicare, Medicaid, VA, TRICARE
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EysuvisView full Eysuvis profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.