| Hypogonadotropic hypogonadism
AndroGel vs Aveed
Side-by-side clinical, coverage, and cost comparison for hypogonadotropic hypogonadism.Deep comparison between: Androgel vs Aveed with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsAveed has a higher rate of injection site reactions vs Androgel based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Aveed but not Androgel, including UnitedHealthcare
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Category
Androgel
Aveed
At A Glance
Topical
Daily
Androgen
IM injection
Every 10 weeks
Androgen
Indications
- Primary hypogonadism
- Hypogonadotropic hypogonadism
- Primary hypogonadism
- Hypogonadotropic hypogonadism
- Klinefelter Syndrome
Dosing
Primary hypogonadism, Hypogonadotropic hypogonadism Starting dose 40.5 mg testosterone (2 pump actuations or one 40.5 mg packet) applied once daily to upper arms and shoulders; titrate between 20.25 mg and 81 mg based on pre-dose morning serum testosterone at days 14 and 28 after starting or adjusting dose.
Primary hypogonadism, Hypogonadotropic hypogonadism, Klinefelter Syndrome 750 mg (3 mL) IM injection deeply into the gluteal muscle at initiation, repeated after 4 weeks, then every 10 weeks thereafter; observe patients for 30 minutes after each injection.
Contraindications
- Carcinoma of the breast
- Known or suspected carcinoma of the prostate
- Pregnancy (can cause virilization of the female fetus)
- Carcinoma of the breast or known or suspected carcinoma of the prostate
- Pregnancy (testosterone causes virilization of the female fetus)
- Known hypersensitivity to AVEED or any of its ingredients (testosterone undecanoate, refined castor oil, benzyl benzoate)
Adverse Reactions
Most common (>=5%) PSA increased
Serious Nonfatal arrhythmias warranting intervention, atrial fibrillation, acute kidney injury, bone fracture
Postmarketing Myocardial infarction, stroke, polycythemia, prostate cancer, venous thromboembolism, sleep apnea, priapism, gynecomastia
Most common (>2%) Acne, injection site pain, prostatic specific antigen increased, estradiol increased, hypogonadism
Serious Pulmonary oil microembolism (POME), anaphylaxis, blood pressure increases, cardiovascular events including non-fatal arrhythmias, atrial fibrillation, and acute kidney injury
Postmarketing Polycythemia, thrombocytopenia, myocardial infarction, stroke, deep venous thrombosis, pulmonary embolism, prostate cancer, gynecomastia, hepatic function abnormalities
Pharmacology
Endogenous androgen replacement; testosterone and dihydrotestosterone (DHT) are responsible for normal growth and development of male sex organs and maintenance of secondary sex characteristics, with male hypogonadism resulting from insufficient testosterone secretion due to gonadal defects (primary) or hypothalamic/pituitary failure (hypogonadotropic).
Testosterone replacement agent; endogenous androgen responsible for normal growth and development of male sex organs and maintenance of secondary sex characteristics including hair distribution, laryngeal enlargement, and body musculature and fat distribution.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Androgel
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (0/12)
Aveed
- Covered on 5 commercial plans
- PA (9/12) · Step Therapy (9/12) · Qty limit (0/12)
UnitedHealthcare
Androgel
- Covered on 4 commercial plans
- PA (5/8) · Step Therapy (0/8) · Qty limit (0/8)
Aveed
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Androgel
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (0/3)
Aveed
- Covered on 0 commercial plans
- PA (2/3) · Step Therapy (2/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Androgel.
$0/fillfill
Aveed Copay Assistance ProgramCommercial or private insurance
Medicare, Medicaid, VA, TRICARE
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AndrogelView full Androgel profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.