| Keratoconjunctivitis Sicca
Cequa vs Lacrisert
Side-by-side clinical, coverage, and cost comparison for keratoconjunctivitis sicca.Deep comparison between: Cequa vs Lacrisert with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsLacrisert has a higher rate of injection site reactions vs Cequa based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Lacrisert but not Cequa, including UnitedHealthcare
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Category
Cequa
Lacrisert
At A Glance
Ophthalmic
Twice daily
Calcineurin inhibitor immunosuppressant
Ophthalmic insert
Once daily
Ocular lubricant
Indications
- Keratoconjunctivitis Sicca
- Dry Eye Syndromes
- Keratoconjunctivitis Sicca
- Exposure keratoconjunctivitis
- Corneal hypoesthesia
- Recurrent erosion of cornea
Dosing
Keratoconjunctivitis Sicca Instill one drop twice daily (approximately 12 hours apart) into each eye; allow a 15-minute interval if used concomitantly with artificial tears; discard vial immediately after use in both eyes.
Dry Eye Syndromes, Keratoconjunctivitis Sicca, Exposure keratoconjunctivitis, Corneal hypoesthesia, Recurrent erosion of cornea One ophthalmic insert in each eye once daily; some patients may require twice daily use for optimal results; insert into the inferior cul-de-sac of the eye beneath the base of the tarsus.
Contraindications
—
- Hypersensitivity to hydroxypropyl cellulose
Adverse Reactions
Most common (>5%) Instillation site pain, conjunctival hyperemia
Other (1-5%) Blepharitis, eye irritation, headache, urinary tract infection
Most common Transient blurring of vision, ocular discomfort or irritation, matting or stickiness of eyelashes, photophobia, hypersensitivity, edema of the eyelids, hyperemia
Pharmacology
Cyclosporine is a calcineurin inhibitor immunosuppressant; when applied topically to the eye, it is thought to act as a partial immunomodulator in patients whose tear production is suppressed due to ocular inflammation associated with keratoconjunctivitis sicca, though the exact mechanism of action is not known.
Ocular lubricant; stabilizes and thickens the precorneal tear film and prolongs tear film breakup time to reduce signs and symptoms of dry eye syndromes, including lubrication and protection of the eye.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Cequa
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
Lacrisert
- Covered on 5 commercial plans
- PA (6/12) · Step Therapy (0/12) · Qty limit (0/12)
UnitedHealthcare
Cequa
- Covered on 4 commercial plans
- PA (1/8) · Step Therapy (0/8) · Qty limit (1/8)
Lacrisert
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Cequa
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (2/3)
Lacrisert
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Cequa.
No savings programs available for Lacrisert.
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LacrisertView full Lacrisert profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.