| Migraine Disorders
Aimovig vs Reyvow
Side-by-side clinical, coverage, and cost comparison for migraine disorders.Deep comparison between: Aimovig vs Reyvow with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsReyvow has a higher rate of injection site reactions vs Aimovig based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Reyvow but not Aimovig, including UnitedHealthcare
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Category
Aimovig
Reyvow
At A Glance
SC injection
Once monthly
CGRP receptor antagonist
Oral
As needed
5-HT1F receptor agonist
Indications
- Migraine Disorders
- Migraine Disorders
Dosing
Migraine Disorders 70 mg SC once monthly; some patients may benefit from 140 mg SC once monthly.
Migraine Disorders 50 mg, 100 mg, or 200 mg orally as needed; no more than one dose in 24 hours; wait at least 8 hours between dosing and driving or operating machinery; swallow tablets whole.
Contraindications
- Serious hypersensitivity to erenumab-aooe or any excipient (reactions have included anaphylaxis and angioedema)
—
Adverse Reactions
Most common (>=3%) Injection site reactions, constipation
Serious Hypersensitivity reactions, constipation with serious complications, hypertension, Raynaud's phenomenon
Postmarketing Hypersensitivity reactions (rash, angioedema, anaphylaxis), constipation with serious complications, oral mucosal ulceration, rash, alopecia, hypertension, Raynaud's phenomenon
Most common (>=2%) dizziness, fatigue, paresthesia, sedation, nausea and/or vomiting, muscle weakness
Serious hypersensitivity reactions including angioedema, rash, and photosensitivity reaction
Pharmacology
CGRP receptor antagonist; human monoclonal antibody that binds to the calcitonin gene-related peptide (CGRP) receptor and antagonizes CGRP receptor function.
5-HT1F receptor agonist; lasmiditan binds with high affinity to the 5-HT1F receptor and presumably exerts its therapeutic effects in migraine through agonist activity at this receptor, though the precise mechanism is unknown.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Aimovig
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (5/12) · Qty limit (1/12)
Reyvow
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (10/12)
UnitedHealthcare
Aimovig
- Covered on 4 commercial plans
- PA (6/8) · Step Therapy (6/8) · Qty limit (1/8)
Reyvow
- Covered on 4 commercial plans
- PA (6/8) · Step Therapy (5/8) · Qty limit (4/8)
Humana
Aimovig
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (2/3)
Reyvow
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (3/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
$5/momo
Aimovig CoPay ProgramCommercial or private insurance
Medicare, Medicaid, VA, TRICARE
No savings programs available for Reyvow.
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AimovigView full Aimovig profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.