| Primary hypogonadism
Jatenzo vs Tlando
Side-by-side clinical, coverage, and cost comparison for primary hypogonadism.Deep comparison between: Jatenzo vs Tlando with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsTlando has a higher rate of injection site reactions vs Jatenzo based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Tlando but not Jatenzo, including UnitedHealthcare
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Category
Jatenzo
Tlando
At A Glance
Oral
Twice daily
Androgen
Oral
Twice daily
Androgen
Indications
- Primary hypogonadism
- Hypogonadotropic hypogonadism
- Primary hypogonadism
- Hypogonadotropic hypogonadism
Dosing
Primary hypogonadism, Hypogonadotropic hypogonadism Starting dose 237 mg orally twice daily (morning and evening) with food; dose adjusted between 158 mg and 396 mg twice daily based on serum testosterone concentration measured 6 hours after the morning dose.
Primary hypogonadism, Hypogonadotropic hypogonadism 225 mg (two 112.5 mg capsules) orally twice daily with food, once in the morning and once in the evening; monitor serum testosterone 8-9 hours after morning dose at 3-4 weeks and periodically thereafter.
Contraindications
- Carcinoma of the breast or known or suspected carcinoma of the prostate
- Pregnancy
- Known hypersensitivity to JATENZO or any of its ingredients
- Carcinoma of the breast or known or suspected carcinoma of the prostate
- Pregnancy (testosterone can cause virilization of the female fetus)
- Known hypersensitivity to testosterone undecanoate or any of TLANDO's ingredients
Adverse Reactions
Most common (>=2%) Headache, hematocrit increased, hypertension, HDL decreased, nausea
Postmarketing Myocardial infarction, stroke, venous thromboembolism
Most common (>=2%) increased blood prolactin, hypertension, increased hematocrit, upper respiratory tract infection, weight increased, headache, musculoskeletal pain
Serious polycythemia, venous thromboembolism, worsening of benign prostatic hyperplasia and potential risk of prostate cancer, blood pressure increases, hepatic adverse effects, edema, sleep apnea, gynecomastia, lipid changes, hypercalcemia
Postmarketing myocardial infarction, stroke, venous thromboembolism
Pharmacology
Testosterone undecanoate is a prodrug ester of testosterone; after oral absorption via intestinal lymphatics, endogenous esterases cleave the ester bond to release active testosterone, which binds androgen receptors to support normal male sexual development and maintenance of secondary sex characteristics.
Androgen; testosterone undecanoate is a lipophilic ester of testosterone that, after oral absorption primarily via the lymphatic system (bypassing first-pass hepatic metabolism), is converted to testosterone, which is responsible for normal growth and development of male sex organs and maintenance of secondary sex characteristics.
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Most Common Insurance
Anthem BCBS
Jatenzo
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (9/12) · Qty limit (10/12)
Tlando
- Covered on 5 commercial plans
- PA (9/12) · Step Therapy (9/12) · Qty limit (10/12)
UnitedHealthcare
Jatenzo
- Covered on 4 commercial plans
- PA (1/8) · Step Therapy (0/8) · Qty limit (0/8)
Tlando
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Jatenzo
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (2/3) · Qty limit (2/3)
Tlando
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (2/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Jatenzo.
No savings programs available for Tlando.
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JatenzoView full Jatenzo profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.