| Rosacea

Epsolay vs Soolantra

Side-by-side clinical, coverage, and cost comparison for rosacea.
Deep comparison between: Epsolay vs Soolantra with Prescriber.AI
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Safety signalsSoolantra has a higher rate of injection site reactions vs Epsolay based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Soolantra but not Epsolay, including UnitedHealthcare
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Epsolay
Soolantra
At A Glance
Topical
Once daily
Oxidizing agent
Topical
Daily
Macrocyclic lactone
Indications
  • Rosacea
  • Rosacea
Dosing
Rosacea Apply a pea-sized amount once daily in a thin layer to each area of the face (forehead, chin, nose, each cheek) on clean and dry skin; avoid eyes, lips, and mouth.
Rosacea Apply a pea-size amount to each affected area of the face (forehead, chin, nose, each cheek) once daily as a thin layer, avoiding the eyes and lips.
Contraindications
  • History of hypersensitivity reactions to benzoyl peroxide or any components of the formulation
—
Adverse Reactions
Most common (>=1%) Application site pain, erythema, pruritus, edema
Most common (<=1%) Skin burning sensation, skin irritation
Postmarketing Contact dermatitis, allergic dermatitis
Pharmacology
Benzoyl peroxide is an oxidizing agent with bactericidal and keratolytic effects; the precise mechanism of action in the treatment of rosacea is unknown.
The mechanism of action of Soolantra cream in treating rosacea lesions is unknown; ivermectin is a semi-synthetic macrocyclic lactone derived from Streptomyces avermitilis fermentation belonging to the avermectin family.
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Most Common Insurance
Anthem BCBS
Epsolay
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (0/12) · Qty limit (9/12)
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Soolantra
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (5/12) · Qty limit (9/12)
View full coverage details ›
UnitedHealthcare
Epsolay
  • Covered on 4 commercial plans
  • PA (1/8) · Step Therapy (1/8) · Qty limit (0/8)
View full coverage details ›
Soolantra
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (0/8) · Qty limit (4/8)
View full coverage details ›
Humana
Epsolay
  • Covered on 0 commercial plans
  • PA (1/3) · Step Therapy (2/3) · Qty limit (2/3)
View full coverage details ›
Soolantra
  • Covered on 0 commercial plans
  • PA (1/3) · Step Therapy (3/3) · Qty limit (2/3)
View full coverage details ›
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Epsolay.
No savings programs available for Soolantra.
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EpsolayView full Epsolay profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.