| Rosacea

Soolantra vs Mirvaso

Side-by-side clinical, coverage, and cost comparison for rosacea.
Deep comparison between: Soolantra vs Mirvaso with Prescriber.AI
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Safety signalsMirvaso has a higher rate of injection site reactions vs Soolantra based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Mirvaso but not Soolantra, including UnitedHealthcare
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Soolantra
Mirvaso
At A Glance
Topical
Daily
Macrocyclic lactone
Topical
Once daily
Alpha-2 adrenergic agonist
Indications
  • Rosacea
  • Rosacea
Dosing
Rosacea Apply a pea-size amount to each affected area of the face (forehead, chin, nose, each cheek) once daily as a thin layer, avoiding the eyes and lips.
Rosacea Apply a pea-sized amount once daily to each of the five areas of the face (central forehead, chin, nose, each cheek) as a thin layer across the entire face, avoiding the eyes and lips; wash hands after applying.
Contraindications
—
  • Hypersensitivity reaction to any component of MIRVASO topical gel (reactions have included angioedema, urticaria, and contact dermatitis)
Adverse Reactions
Most common (<=1%) Skin burning sensation, skin irritation
Postmarketing Contact dermatitis, allergic dermatitis
Most common (>=1%) Erythema, flushing, skin burning sensation, contact dermatitis, dermatitis, skin warmth, paraesthesia, acne, skin pain, blurred vision, nasal congestion
Postmarketing Bradycardia, hypotension, angioedema, hypersensitivity, lip swelling, swollen tongue, throat tightness, urticaria, dizziness, pallor
Pharmacology
The mechanism of action of Soolantra cream in treating rosacea lesions is unknown; ivermectin is a semi-synthetic macrocyclic lactone derived from Streptomyces avermitilis fermentation belonging to the avermectin family.
Brimonidine is a relatively selective alpha-2 adrenergic agonist; topical application of MIRVASO topical gel may reduce facial erythema through direct vasoconstriction.
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Most Common Insurance
Anthem BCBS
Soolantra
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (5/12) · Qty limit (9/12)
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Mirvaso
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (5/12) · Qty limit (0/12)
View full coverage details ›
UnitedHealthcare
Soolantra
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (0/8) · Qty limit (4/8)
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Mirvaso
  • Covered on 4 commercial plans
  • PA (6/8) · Step Therapy (0/8) · Qty limit (0/8)
View full coverage details ›
Humana
Soolantra
  • Covered on 0 commercial plans
  • PA (1/3) · Step Therapy (3/3) · Qty limit (2/3)
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Mirvaso
  • Covered on 0 commercial plans
  • PA (1/3) · Step Therapy (1/3) · Qty limit (0/3)
View full coverage details ›
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Soolantra.
No savings programs available for Mirvaso.
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SoolantraView full Soolantra profile
MirvasoView full Mirvaso profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.