| Tinea cruris
Oxistat vs Luzu
Side-by-side clinical, coverage, and cost comparison for tinea cruris.Deep comparison between: Oxistat vs Luzu with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsLuzu has a higher rate of injection site reactions vs Oxistat based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Luzu but not Oxistat, including UnitedHealthcare
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Category
Oxistat
Luzu
At A Glance
Topical
Once to twice daily
Imidazole antifungal
Topical
Daily
Azole antifungal
Indications
- Tinea Pedis
- Tinea cruris
- Tinea corporis (disorder)
- Tinea Pedis
- Tinea cruris
- Tinea corporis (disorder)
Dosing
Tinea cruris, Tinea corporis (disorder) Apply to affected and immediately surrounding areas once to twice daily for 2 weeks.
Tinea Pedis Apply to affected and immediately surrounding areas once to twice daily for 1 month.
Tinea Pedis Apply a thin layer to the affected area and approximately 1 inch of the immediate surrounding area(s) once daily for 2 weeks.
Tinea cruris, Tinea corporis (disorder) Apply a thin layer to the affected area and approximately 1 inch of the immediate surrounding area(s) once daily for 1 week.
Contraindications
- Hypersensitivity to oxiconazole nitrate or any component of OXISTAT Lotion
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Adverse Reactions
Most common Burning, stinging, pruritus, scaling, tingling, pain, dyshidrotic eczema
Postmarketing Irritation, allergic contact dermatitis, folliculitis, erythema, papules, fissure, maceration, rash, nodules
Most common (<1%) Application site reactions
Postmarketing Contact dermatitis, cellulitis
Pharmacology
Oxiconazole nitrate is an imidazole derivative antifungal whose activity is derived primarily from inhibition of ergosterol biosynthesis, which is critical for cellular membrane integrity in pathogenic fungi.
Luliconazole is an azole antifungal that inhibits ergosterol synthesis by blocking lanosterol demethylase, resulting in decreased ergosterol and accumulation of lanosterol in fungal cell membranes.
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Most Common Insurance
Anthem BCBS
Oxistat
- Covered on 5 commercial plans
- PA (5/12) · Step Therapy (9/12) · Qty limit (9/12)
Luzu
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (9/12) · Qty limit (9/12)
UnitedHealthcare
Oxistat
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (1/8)
Luzu
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (1/8)
Humana
Oxistat
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (0/3) · Qty limit (1/3)
Luzu
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (2/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Oxistat.
No savings programs available for Luzu.
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.