Interleukin-17A Antagonist

Interleukin-17A Antagonists

Ankylosing Spondylitis

Psoriatic Arthritis

<section class="Section" data-sectioncode="34089-3"><a name="section-10"></a><h1>11     DESCRIPTION</h1>Secukinumab, a recombinant human monoclonal IgG1/κ antibody, is an interleukin-17A antagonist. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line. Secukinumab has a molecular mass of approximately 151 kDa; both heavy chains of secukinumab contain oligosaccharide chains.COSENTYX InjectionCOSENTYX injection is a sterile, preservative-free, clear to slightly opalescent, colorless to slightly yellow solution for subcutaneous use. COSENTYX is supplied in a single-dose Sensoready pen with a 27-gauge fixed ½-inch needle, or a single-dose prefilled syringe with a 27-gauge fixed ½-inch needle. The removable cap of the COSENTYX Sensoready pen or prefilled syringe contains natural rubber latex.Each COSENTYX Sensoready pen or prefilled syringe contains 150 mg of secukinumab formulated in: L-histidine/histidine hydrochloride monohydrate (3.103 mg), L-methionine (0.746 mg), polysorbate 80 (0.2 mg), trehalose dihydrate (75.67 mg), and Sterile Water for Injection, USP, at pH of 5.8.Each COSENTYX 75 mg/0.5 mL prefilled syringe contains 75 mg of secukinumab formulated in: L-histidine/histidine hydrochloride monohydrate (1.552 mg), L-methionine (0.373 mg), polysorbate 80 (0.1 mg), trehalose dihydrate (37.83 mg), and Sterile Water for Injection, USP, at pH of 5.8. COSENTYX for InjectionCOSENTYX for injection is supplied as a sterile, preservative free, white to slightly yellow, lyophilized powder in single-dose vials for subcutaneous use after reconstitution. Each COSENTYX vial contains 150 mg of secukinumab formulated in L-histidine/histidine hydrochloride monohydrate (4.656 mg), polysorbate 80 (0.6 mg), and sucrose (92.43 mg). Following reconstitution with 1 mL Sterile Water for Injection, USP, the resulting pH is approximately 5.8.</section>

COSENTYX

0.5 ML secukinumab 150 MG/ML Prefilled Syringe

0.5 ML secukinumab 150 MG/ML Prefilled Syringe [Cosentyx]

1 ML secukinumab 150 MG/ML Auto-Injector

1 ML secukinumab 150 MG/ML Auto-Injector [Cosentyx]

1 ML secukinumab 150 MG/ML Prefilled Syringe

1 ML secukinumab 150 MG/ML Prefilled Syringe [Cosentyx]

Cosentyx

secukinumab

UWisconsin Health Pharmacy Services

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Cosentyx | UWisconsin Health Pharmacy Services | limited distribution

Does Cosentyx have a limited distribution partnership with UWisconsin Health Pharmacy Services?

Which health plans does UWisconsin Health Pharmacy Services have contracts with?

Does UWisconsin Health Pharmacy Services work closely with Cosentyx and Novartis Pharmaceuticals Corporation?

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