Integrin Receptor Antagonists

Integrin Receptor Antagonist

Colitis, Ulcerative

Crohn Disease

Enteritis

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-9"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Vedolizumab, an integrin receptor antagonist, is a humanized IgG<span class="Sub">1 </span>monoclonal antibody produced in Chinese hamster ovary cells that binds to the human α4β7 integrin. ENTYVIO has an approximate molecular weight of 147 kilodaltons.</p><div class="Section" data-sectioncode="42229-5"><a name="section-9.1"></a><p></p><p class="First"><span class="Italics Underline">Intravenous ENTYVIO</span></p><p>ENTYVIO (vedolizumab) for injection is supplied as a sterile, white to off-white, preservative-free, lyophilized cake for intravenous infusion. After reconstitution with 4.8 mL Sterile Water for Injection, USP, 0.9% Sodium Chloride Injection, USP, or Lactated Ringer's Injection, USP, the resulting concentration is 60 mg/mL with a deliverable volume of 5 mL (300 mg) and the resulting pH is approximately 6.3.</p><p>Each single-dose vial contains 300 mg vedolizumab, arginine hydrochloride (131.7 mg), histidine (23 mg), histidine monohydrochloride (21.4 mg), polysorbate 80 (3 mg), and sucrose (500 mg).</p></div><div class="Section" data-sectioncode="42229-5"><a name="section-9.2"></a><p></p><p class="First"><span class="Italics Underline">Subcutaneous ENTYVIO</span></p><p>ENTYVIO (vedolizumab) injection is supplied as a sterile, clear to moderately opalescent, colorless to slightly yellow, preservative-free solution for subcutaneous administration.</p><p>Each single-dose prefilled syringe or single-dose prefilled pen (ENTYVIO PEN) contains 108 mg vedolizumab, arginine hydrochloride (17.77 mg), citric acid monohydrate (0.18 mg), histidine (3.86 mg), histidine monohydrochloride (1.86 mg), polysorbate 80 (1.35 mg), sodium citrate dihydrate (4.71 mg) and Sterile Water for Injection, USP, at a pH of 6.5.</p></div></section>

Entyvio

vedolizumab

vedolizumab 300 MG Injection

vedolizumab 300 MG Injection [Entyvio]

0.68 ML vedolizumab 159 MG/ML Prefilled Syringe

0.68 ML vedolizumab 159 MG/ML Prefilled Syringe [Entyvio]

0.68 ML vedolizumab 159 MG/ML Auto-Injector

0.68 ML vedolizumab 159 MG/ML Auto-Injector [Entyvio]

Reliance Rx

ACTEMRA

ADAKVEO

ADCETRIS

AFINITOR

AKYNZEO

ALDURAZYME

ambrisentan (LETAIRIS)

ARANESP

AUBAGIO

AVASTIN

azacitidine (VIDAZA)

BENLYSTA

BETHKIS

BEOVU

bosentan (TRACLEER)

CEREZYME

CINQAIR

COSENTYX

decitabine (DACOGEN)

DARZALEX

dimethyl fumarate (TECFIDERA)

doxorubicin (ADRIAMYCIN

DOXIL)

DYSPORT

EGRIFTA

ELAPRASE

ELZONRIS

EMPLICITI

ENBREL

ENSPRYNG

ENTYVIO

ENVARSUS XR

erlotinib (TARCEVA)

EYLEA

FABRAZYME

FIBRYGA

FIRAZYR

lutamide (EULEXIN)

GAZYVA

HERCEPTIN HYLECTA

HIZENTRA

KADCYLA

KITABIS PAK

Lucentis

LUMIZYME

MAYZENT

mercaptopurine (PURIXAN)

NAGLAZYME

NEXVIAZYME

NINLARO

NUWIQ

OCREVUS

ODOMZO

OLUMIANT

ONCASPAR

ONTRUZANT

ONUREG

OPDIVO

PERJETA

PHESGO

PLEGRIDY

POLIVY

PONVORY

PURIXAN

RADICAVA

RETACRIT

RITUXAN

RITUXAN HYCELA

RYBREVANT

SOMATULINE DEPOT

sorafenib (NEXAVAR)

Susvimo

sunitinib (SUTENT)

TALTZ

TARCEVA

TECENTRIQ

TECFIDERA

tetrabenazine (XENAZINE)

TROGARZO

VANTAS

VIMIZIM

VPRIV

VUMERITY

VYVGART

XEMBIFY

YERVOY

ZELBORAF

ZEPOSIA

ZYKADIA

Entyvio | Reliance Rx

Which health plans does Reliance Rx have contracts with?

Does Reliance Rx work closely with Entyvio and Takeda Pharmaceuticals America, Inc.?

Does Reliance Rx offer services for Entyvio patients?

What conditions does Reliance Rx support?

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