HER2/Neu/cerbB2 Antagonists

HER2/neu Receptor Antagonist

Breast Neoplasms

Gastrointestinal Neoplasms

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-9"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Trastuzumab is a humanized IgG1 kappa monoclonal antibody that selectively binds with high affinity to the extracellular domain of the human epidermal growth factor receptor 2 protein, HER2.  Trastuzumab is produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary) culture.</p><p>Herceptin (trastuzumab) for injection is a sterile, white to pale yellow, preservative-free lyophilized powder with a cake-like appearance, for intravenous administration.  </p><p>Each single-dose vial of Herceptin delivers 150 mg trastuzumab, 136.2 mg α,α-trehalose dihydrate, 3.4 mg L-histidine HCl monohydrate, 2.2 mg L-histidine, and 0.6 mg polysorbate 20. Reconstitution with 7.4 mL of sterile water for injection (SWFI) yields a solution containing 21 mg/mL trastuzumab that delivers 7.15 mL (150 mg trastuzumab), at a pH of approximately 6.</p></section>

Herceptin

trastuzumab 150 MG Injection

trastuzumab 150 MG Injection [Herceptin]

trastuzumab 21 MG/ML Injectable Solution

trastuzumab 21 MG/ML Injectable Solution [Herceptin]

trastuzumab

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information

Submit MSL Request

Reimbursement Information 

Pharmacy List 

How To Order Herceptin 

Billing & Coding Guide: First-, Second- and Third-line Metastatic Breast Cancer

Billing & Coding Guide: Metastatic Gastric Cancer

Coverage Authorization Request

Coverage Authorization Appeals

Letter of Medical Necessity 

Prescriber Service & Patient Consent Form 

Prescriber Service Form - Online Portal 

Patient Consent Form - English 

Patient Consent Form - Spanish 

Genentech Prescriber Foundation Form

My Patient Solutions - HCP Portal (for managing service requests)

Enroll in Patient Savings Program 

Formulary Information

About Herceptin

Breast Cancer & Herceptin

Stomach Cancer & Herceptin

Patient Resources: Independent Financial Support Programs

Instructions for Use: Early Breast Cancer 

Instructions for Use: Metastatic Breast Cancer

Instructions For Use: Stomach Cancer 

Receiving Herceptin: Early Breast Cancer 

Receiving Herceptin: Metastatic Breast Cancer 