CD20-directed Antibody Interactions

CD20-directed Cytolytic Antibody

Leukemia, Lymphoid

<section class="Section" data-sectioncode="34089-3"><a name="section-9"></a><p></p><h1>11     DESCRIPTION</h1><p class="First">Ofatumumab is a recombinant human monoclonal immunoglobulin G1 (IgG1) antibody that binds to human CD20 expressed on B-cells. Ofatumumab is produced in a murine NS0 cell line and consists of two IgG1 heavy chains and two kappa light chains with a molecular weight of approximately 146 kDa.</p><p>KESIMPTA (ofatumumab) injection is a sterile, preservative-free solution for subcutaneous use.</p><p>Each 20 mg/0.4 mL KESIMPTA Sensoready Pen or prefilled syringe delivers 0.4 mL of solution. Each 0.4 mL contains 20 mg of ofatumumab, and arginine (4 mg), disodium edetate (0.007 mg), polysorbate 80 (0.08 mg), sodium acetate trihydrate (2.722 mg), sodium chloride (1.192 mg), and Water for Injection, USP with a pH of 5.5. Hydrochloric acid may have been added to adjust pH.</p></section>

KESIMPTA

0.4 ML ofatumumab 50 MG/ML Pen Injector

Kesimpta

0.4 ML ofatumumab 50 MG/ML Pen Injector [Kesimpta]

ofatumumab

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information 

Medication Guide 

Submit MSL Request 

Pharmacy List 

Online Sample Form (Contact Rep)

Coverage Authorization Request 

Coverage Authorization Appeals: New to Treatment 

Coverage Authorization Appeals: Change of Treatment 

Letter of Medical Necessity: New to Treatment 

Letter of Medical Necessity: Change of Treatment 

Alongside Kesimpta Start Form 

Alongside Kesimpta Start Form: Online (Through CoverMyMeds)

Patient Authorization Form 

Patient Authorization Form - Spanish

Enroll in Patient Savings Program

Bridge Program 

Starting Patients on Kesimpta 

Other HCP Resources: Videos 

About Kesimpta 

Taking Kesimpta

Side Effects 

Patient Stories

FAQs: Multiple Sclerosis

Alongside Kesimpta Support Program

Patient Resources

Instructions for Use: Multiple Sclerosis 