Alopecia Areata

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">LITFULO (ritlecitinib) capsules are formulated with ritlecitinib tosylate, a kinase inhibitor.</p><p>Ritlecitinib tosylate is a white to off white to pale pink solid which is freely soluble in water. The chemical name is 1-{(2S,5R)-2-Methyl-5-[(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}prop-2-en-1-one 4 methylbenzene-1-sulfonic acid. </p><p>The molecular formula for ritlecitinib tosylate is C<span class="Sub">22</span>H<span class="Sub">27</span>N<span class="Sub">5</span>O<span class="Sub">4</span>S. The molecular weight is 457.55 g/mol and its structural formula is:</p><div class="Figure"><a name="id1173"></a><img alt="Chemical Structure" src="litfulo-01.jpg"/></div><p>LITFULO is supplied for oral administration as a 50 mg immediate-release capsule. Each capsule contains 50 mg ritlecitinib (equivalent to 80.13 mg ritlecitinib tosylate) and the following inactive ingredients: crospovidone, glyceryl dibehenate, lactose monohydrate, microcrystalline cellulose, and hypromellose (HPMC) capsule shells. The yellow/blue, opaque capsule shells contain Brilliant blue FCF – FD&amp;C Blue, hypromellose, titanium dioxide, and yellow iron oxide.</p></section>

Litfulo

ritlecitinib

ritlecitinib 50 MG Oral Capsule

ritlecitinib 50 MG Oral Capsule [Litfulo]

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