Oxycontin Drug Interactions: 95 Major, 415 Moderate
Oxycontin (Oxycodone Hydrochloride) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Oxycontin. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Oxycodone can be increased when combined with Abatacept.
Level 1 evidence
Abiraterone
The metabolism of Oxycodone can be decreased when combined with Abiraterone.
Level 1 evidence
Acebutolol
The metabolism of Oxycodone can be decreased when combined with Acebutolol.
Level 2 evidence
Acetazolamide
The risk or severity of CNS depression can be increased when Oxycodone is combined with Acetazolamide.
Level 2 evidence
Aclidinium
The risk or severity of adverse effects can be increased when Aclidinium is combined with Oxycodone.
Level 1 evidence
Adagrasib
The metabolism of Oxycodone can be decreased when combined with Adagrasib.
Level 2 evidence
Adalimumab
The metabolism of Oxycodone can be increased when combined with Adalimumab.
Level 1 evidence
Alfentanil
The risk or severity of adverse effects can be increased when Oxycodone is combined with Alfentanil.
Level 1 evidence
Almotriptan
The risk or severity of CNS depression can be increased when Oxycodone is combined with Almotriptan.
Level 2 evidence
Alosetron
The risk or severity of CNS depression can be increased when Oxycodone is combined with Alosetron.
Level 2 evidence
Alprazolam
The risk or severity of adverse effects can be increased when Oxycodone is combined with Alprazolam.
Level 1 evidence
Amantadine
The risk or severity of adverse effects can be increased when Amantadine is combined with Oxycodone.
Level 1 evidence
Enter your NPI to unlock 6 major interactions for Oxycontin
Oxycontin (Oxycodone Hydrochloride) has 943 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Oxycontin (Oxycodone Hydrochloride) has 95 major, 415 moderate, and 433 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Oxycontin. Always confirm against the full prescribing information.