Cytochrome P450 2B6 Inhibitors

Cytochrome P450 3A4 Inhibitors

Cytochrome P450 17A1 Inhibitors

P-Glycoprotein Inhibitors

Organic Cation Transporter 2 Inhibitors

Cytochrome P450 2C8 Inhibitors

Multidrug and Toxin Extrusion Transporter 1 Inhibitors

Cortisol Synthesis Inhibitor

Cytochrome P450 11B1 Inhibitors

Cytochrome P450 11A1 Inhibitors

Azole Antifungal

Cytochrome P450 3A5 Inhibitors

Blastomycosis

Candidiasis, Chronic Mucocutaneous

Candidiasis, Cutaneous

Candidiasis, Oral

Candidiasis, Vulvovaginal

Coccidioidomycosis

Histoplasmosis

Leishmaniasis

Mycoses

Paracoccidioidomycosis

Dermatitis, Seborrheic

Tinea Pedis

Tinea Versicolor

Acanthamoeba Keratitis

<section class="Section" data-sectioncode="34089-3"><a name="id_link_d4c69d16-965a-15e0-e053-2995a90ac2cc"></a><a name="section-10"></a><h1>11 DESCRIPTION</h1>RECORLEV (levoketoconazole) tablets contain levoketoconazole as the active ingredient. Levoketoconazole is the 2S,4R- enantiomer derived from racemic ketoconazole and is a cortisol synthesis inhibitor.The chemical name of levoketoconazole is 2S,4R cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl] methoxyl]phenyl] piperazine.The molecular formula of levoketoconazole is C26H28Cl2N4O4 with a molecular mass of 531.43 g/mol.<img alt="Structure" src="molecular-structure-recorlev.jpg"/>Levoketoconazole is a white or almost white crystalline powder. It is very slightly soluble in water but soluble in aqueous solutions below pH 2.RECORLEV tablets for oral administration contain 150 mg of levoketoconazole and the following inactive ingredients: colloidal silicon dioxide, lactose monohydrate, magnesium stearate, modified corn starch, and silicified microcrystalline cellulose. The non-functional pink film-coating contains iron oxide red, macrogol/polyethylene glycol 3350, polyvinyl alcohol partially hydrolyzed, talc, and titanium dioxide. The tablets are printed with a black imprinting ink that contains ammonium hydroxide 28%, ferrosoferric oxide, isopropyl alcohol, propylene glycol, and shellac glaze 45% (20% esterified) in ethanol.</section>

Recorlev

levoketoconazole

levoketoconazole 150 MG Oral Tablet

levoketoconazole 150 MG Oral Tablet [Recorlev]

ketoconazole

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information 

Medication Guide 

Submit MSL Request 

Pharmacy List 

Coverage Authorization Request 

Coverage Authorization Appeals 

Letter of Medical Necessity 

Formulary Exception Letter 

Recorlev Prescription Start Form

Enroll in Patient Savings Program 

Other HCP Resources

About Recorlev 

Taking Recorlev 

Xeris Care Connection Support Program 

Instructions For Use: Endogenous Hypercortisolemia due to Cushing’s Syndrome