Spravato Drug Interactions: 117 Major, 558 Moderate
Spravato (Esketamine Hydrochloride) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Spravato. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Esketamine can be increased when combined with Abatacept.
Level 1 evidence
Abrocitinib
The metabolism of Abrocitinib can be decreased when combined with Esketamine.
Level 2 evidence
Aceclofenac
The risk or severity of hypertension can be increased when Esketamine is combined with Aceclofenac.
Level 1 evidence
Acenocoumarol
The metabolism of Acenocoumarol can be increased when combined with Esketamine.
Level 1 evidence
Acetazolamide
The risk or severity of adverse effects can be increased when Acetazolamide is combined with Esketamine.
Level 1 evidence
Acetylsalicylic acid
The risk or severity of hypertension can be increased when Esketamine is combined with Acetylsalicylic acid.
Level 1 evidence
Acoramidis
The metabolism of Esketamine can be decreased when combined with Acoramidis.
Level 2 evidence
Adagrasib
The metabolism of Esketamine can be decreased when combined with Adagrasib.
Level 2 evidence
Adalimumab
The metabolism of Esketamine can be increased when combined with Adalimumab.
Level 1 evidence
Aficamten
The metabolism of Aficamten can be decreased when combined with Esketamine.
Level 2 evidence
Albendazole
The metabolism of Albendazole can be increased when combined with Esketamine.
Level 2 evidence
Albuterol
The risk or severity of hypertension can be increased when Esketamine is combined with Salbutamol.
Level 1 evidence
Enter your NPI to unlock 17 major interactions for Spravato
Spravato (Esketamine Hydrochloride) has 737 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Spravato (Esketamine Hydrochloride) has 117 major, 558 moderate, and 62 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Spravato. Always confirm against the full prescribing information.