CD3-directed Antibody Interactions

CD3-directed Antibody

Diabetes Mellitus, Type 1

<section class="Section" data-sectioncode="34089-3"><a name="s11"></a><a name="section-8"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Teplizumab-mzwv is a CD3-directed monoclonal antibody (humanized IgG1 kappa) that has a molecular weight of approximately 150 kilodalton (kDa) and is expressed from a recombinant Chinese hamster ovary (CHO) cell line.</p><p>TZIELD (teplizumab-mzwv) injection is supplied as a sterile, preservative-free, clear and colorless solution in a 2 mg/2 mL (1 mg/mL) single-dose vial for intravenous use. Each mL contains 1 mg of teplizumab-mzwv, dibasic sodium phosphate (0.26 mg), monobasic sodium phosphate (0.98 mg), polysorbate 80 (0.05 mg), sodium chloride (8.78 mg), and water for injection. The pH is 6.1.</p></section>

TZIELD

teplizumab

teplizumab-mzwv

2 ML teplizumab-mzwv 1 MG/ML Injection

Tzield

2 ML teplizumab-mzwv 1 MG/ML Injection [Tzield]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information

Medication Guide 

Pharmacy List 

How To Order Tzield 

Billing & Coding Guide 

Coverage Authorization Request 

Coverage Authorization Appeals 

Prevention Bio Compass Tzield Patient Start Form 

Enroll in Patient Savings Program 

Other HCP Resources 

Prevention Bio Compass Navigator Support Program 

About Tzield

Instructions For Use: Type 1 Diabetes 

Receiving Tzield

FAQs: Type I Diabetes

Patient Resources

Tzield Compass Support Program