Vesicular Monoamine Transporter 2 Inhibitors

Vesicular Monoamine Transporter 2 Inhibitor

Huntington Disease

Hyperkinesis

<section class="Section" data-sectioncode="34089-3"><a name="LINK_39d98581-8734-4edb-824a-e08ad6756b9d"></a><a name="section-11"></a><p></p><h1>11   DESCRIPTION</h1><p class="First">XENAZINE (tetrabenazine) is a monoamine depletor for oral administration. The molecular weight of tetrabenazine is 317.43; the pKa is 6.51. Tetrabenazine is a hexahydro-dimethoxy-benzoquinolizine derivative and has the following chemical name: cis rac –1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one.</p><p>The empirical formula C<span class="Sub">19</span>H<span class="Sub">27</span>NO<span class="Sub">3 </span>is represented by the following structural formula:</p><div class="Figure"><img alt="Chemical Structure" src="xenazine--tetrabenazine-tablet-1.jpg"/></div><p>Tetrabenazine is a white to slightly yellow crystalline powder that is sparingly soluble in water and soluble in ethanol.</p><p>Each XENAZINE (tetrabenazine) tablet contains either 12.5 or 25 mg of tetrabenazine as the active ingredient. </p><p>XENAZINE (tetrabenazine) tablets contain tetrabenazine as the active ingredient and the following inactive ingredients: lactose, magnesium stearate, maize starch, and talc.  The 25 mg strength tablet also contains yellow iron oxide as an inactive ingredient. </p><p>XENAZINE (tetrabenazine) tablets are supplied as a yellowish-buff, scored tablet containing 25 mg of tetrabenazine or as a white, non-scored tablet containing 12.5 mg of tetrabenazine.</p></section>

Xenazine

tetrabenazine

tetrabenazine 25 MG Oral Tablet

tetrabenazine 25 MG Oral Tablet [Xenazine]

tetrabenazine 12.5 MG Oral Tablet

tetrabenazine 12.5 MG Oral Tablet [Xenazine]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information 

Medication Guide 

Submit MSL Request 

Pharmacy List 

Coverage Authorization Request 

Coverage Authorization Appeals 

Xenazine Treatment & Prescription Form 

Enroll in Patient Savings Program 

Instructions For Use: Chorea Associated with Huntington’s Disease