RANK Ligand Blocking Activity

RANK Ligand Inhibitor

Osteoporosis, Postmenopausal

Osteoporotic Fractures

<section class="Section" data-sectioncode="34089-3"><a name="section-9"></a><p></p><h1><span class="Bold">11</span><span class="Bold">         DESCRIPTION</span></h1><p class="First">Xgeva (denosumab) is a human IgG2 monoclonal antibody that binds to human RANKL.  Denosumab has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells.</p><p>Xgeva is a sterile, preservative-free, clear, colorless to pale yellow solution.</p><p>Each single-dose vial of Xgeva contains 120 mg denosumab, acetate (18 mM), polysorbate 20 (0.01%), sorbitol (4.6%), Water for Injection (USP), and sodium hydroxide to a pH of 5.2.</p></section>

XGEVA

1.7 ML denosumab 70 MG/ML Injection

Xgeva

1.7 ML denosumab 70 MG/ML Injection [Xgeva]

denosumab

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event

Prescribing Information

Submit MSL Request

Pharmacy List 

Reimbursement Information

Billing & Coding - Hospital Outpatient 

Billing & Coding - Physician Office 

Benefit Verification

Coverage Authorization Request 

Coverage Authorization Appeals 

Letter of Medical Necessity

Amgen SupportPlus Enrollment Form 

Enroll in Patient Savings Program 

Patient Stories 

Other HCP Resources 

Other HCP Resources - Patient Education

Breast Cancer Patient Brochure

Prostate Cancer Patient Brochure

Multiple Myeloma Patient Brochure

Appointment Tracker 

ONJ Handout 

Hypocalcemia Handout

About Xgeva 

Discussion Guide 

Receiving Xgeva

Patient Resources 

FAQs: Prevention of Skeletal-Related Events in Patients With Multiple Myeloma and Bone Metastases From Solid Tumors

Instructions For Use: Prevention of Skeletal-Related Events in Patients With Multiple Myeloma and Bone Metastases From Solid Tumors

Xgeva Cares Enrollment - Patient Support Program 