Central Nervous System Depressant

Cataplexy

<section class="Section" data-sectioncode="34089-3"><a name="i4i_description_id_f8b62f4e-a47e-4a60-85f1-71e098162a28"></a><a name="section-11"></a><h1>11 DESCRIPTION</h1>XYWAV oral solution contains oxybate, a CNS depressant. The chemical name of oxybate is gamma-hydroxybutyrate (GHB). XYWAV contains a mixture of calcium oxybate, magnesium oxybate, potassium oxybate, and sodium oxybate equivalent to 0.5 g/mL, which corresponds to 0.413 g/mL oxybate.Each mL of XYWAV contains: 0.234 g calcium oxybate, Ca(C4H7O3)2; 0.096 g magnesium oxybate, Mg(C4H7O3)2; 0.13 g potassium oxybate, K(C4H7O3); and 0.04 g sodium oxybate, Na(C4H7O3) in dissociated form in the solution. The molecular weights of each are as follows: calcium oxybate is 246.3, magnesium oxybate is 230.5, potassium oxybate is 142.2, and sodium oxybate is 126.1.The chemical structure is:<a name="id-1670245594"></a><img alt="chemical structure" src="image-01.jpg"/> y=1 for Na+ and K+; y=2 for Mg2+ and Ca2+The inactive ingredients are purified water and sucralose. XYWAV contains no ingredient made from a gluten‑containing grain (wheat, barley, or rye).</section>

XYWAV

oxybate

calcium oxybate

magnesium oxybate

potassium oxybate

calcium oxybate 234 MG/ML / magnesium oxybate 96 MG/ML / potassium oxybate 130 MG/ML / sodium oxybate 40 MG/ML Oral Solution [Xywav]

calcium oxybate 234 MG/ML / magnesium oxybate 96 MG/ML / potassium oxybate 130 MG/ML / sodium oxybate 40 MG/ML Oral Solution

calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate

Xywav

sodium oxybate

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information 

Medication Guide 

Submit MSL Request 

Pharmacy List 

Reimbursement Information 

Formulary Information 

Coverage Authorization Request 

Coverage Authorization Appeals 

Guide to Completing Prior Authorization: Narcolepsy 

Guide to Completing Prior Authorization: Idiopathic Hypersomnia

Formulary Exception Process Guide

Letter of Medical Necessity: Narcolepsy 

Letter of Medical Necessity: Idiopathic Hypersomnia

Enroll in Patient Savings Program 

Enroll in Bridge Program 

Quick Start Voucher Program 

JazzCares Patient Assistance Program

Other HCP Resources: Narcolepsy

Other HCP Resources: Idiopathic Hypersomnia

About Xywav: Narcolepsy 

FAQs: Narcolepsy 

Getting Xywav: Narcolepsy

Taking Xywav: Narcolepsy

Side Effects: Narcolepsy

Patient Stories: Narcolepsy

Patient Resources: Narcolepsy 

Doctor Discussion Guide: Narcolepsy

Patient Brochure: Narcolepsy

Instructions For Use: Narcolepsy 

About Xywav: Idiopathic Hypersomnia 

Side Effects: Idiopathic Hypersomnia 

Taking Xywav: Idiopathic Hypersomnia

Getting Xywav: Idiopathic Hypersomnia

FAQs: Idiopathic Hypersomnia 

Patient Resources: Idiopathic Hypersomnia 

Instructions For Use: Idiopathic Hypersomnia 

Doctor Discussion Guide: Idiopathic Hypersomnia

Patient Brochure: Idiopathic Hypersomnia 

Epworth Sleepiness Scale Questionnaire

Idiopathic Hypersomnia Severity Scale (IHSS) Questionnaire

App Download 

Jazz Cares Support Program 