Isocitrate Dehydrogenase 1 Inhibitors [MoA] class drugs

2 results
  • tibsovo - ivosidenib tablet, film coated

    (Ivosidenib)
    Servier Pharmaceutical Llc
    Tibsovo is an IDH1 inhibitor for adults with susceptible IDH1 mutations. Indicated for newly diagnosed AML in patients 75+ or unfit for intensive chemotherapy, relapsed or refractory AML, relapsed or refractory myelodysplastic syndromes, and previously treated locally advanced or metastatic cholangiocarcinoma.
  • voranigo - vorasidenib tablet, film coated

    (Vorasidenib)
    Servier Pharmaceuticals Llc
    Voranigo treats adults and pediatric patients 12 and older with Grade 2 astrocytoma or oligodendroglioma harboring a susceptible IDH1 or IDH2 mutation, as confirmed by an FDA-approved test, following surgery including biopsy, sub-total, or gross total resection.