| Rosacea

Rhofade vs Soolantra

Side-by-side clinical, coverage, and cost comparison for rosacea.
Deep comparison between: Rhofade vs Soolantra with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.
Safety signalsSoolantra has a higher rate of injection site reactions vs Rhofade based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Soolantra but not Rhofade, including UnitedHealthcare
Sign up to reveal the full AI analysis
Rhofade
Soolantra
At A Glance
Topical
Daily
Alpha-1A adrenoceptor agonist
Topical
Daily
Macrocyclic lactone
Indications
  • Rosacea
  • Rosacea
Dosing
Rosacea Apply a pea-sized amount once daily in a thin layer to cover the entire face (forehead, nose, each cheek, and chin), avoiding the eyes and lips; wash hands immediately after applying.
Rosacea Apply a pea-size amount to each affected area of the face (forehead, chin, nose, each cheek) once daily as a thin layer, avoiding the eyes and lips.
Contraindications
—
—
Adverse Reactions
Most common (>=1%) application site dermatitis, worsening inflammatory lesions of rosacea, application site pruritus, application site erythema, application site pain
Most common (<=1%) Skin burning sensation, skin irritation
Postmarketing Contact dermatitis, allergic dermatitis
Pharmacology
Oxymetazoline is an alpha 1A adrenoceptor agonist that acts as a vasoconstrictor when applied topically to the face.
The mechanism of action of Soolantra cream in treating rosacea lesions is unknown; ivermectin is a semi-synthetic macrocyclic lactone derived from Streptomyces avermitilis fermentation belonging to the avermectin family.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Rhofade
  • Covered on 5 commercial plans
  • PA (9/12) · Step Therapy (6/12) · Qty limit (9/12)
View full coverage details ›
Soolantra
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (5/12) · Qty limit (9/12)
View full coverage details ›
UnitedHealthcare
Rhofade
  • Covered on 4 commercial plans
  • PA (5/8) · Step Therapy (0/8) · Qty limit (1/8)
View full coverage details ›
Soolantra
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (0/8) · Qty limit (4/8)
View full coverage details ›
Humana
Rhofade
  • Covered on 0 commercial plans
  • PA (1/3) · Step Therapy (2/3) · Qty limit (3/3)
View full coverage details ›
Soolantra
  • Covered on 0 commercial plans
  • PA (1/3) · Step Therapy (3/3) · Qty limit (2/3)
View full coverage details ›
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Rhofade.
No savings programs available for Soolantra.
Compare Other Drugs
Let us handle your prior authsJust enter your patient's info and we'll:
  • Verify eligibility with the payer.
  • Pull the right PA forms directly from the payer.
  • Submit, track & send live updates to your dashboard.
Utilize patient records to autofill forms with our AI in seconds.
Free to start · HIPAA compliant
Next Steps for Your Patient
RhofadeView full Rhofade profile
SoolantraView full Soolantra profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.