| Rosacea
Soolantra vs Rhofade
Side-by-side clinical, coverage, and cost comparison for rosacea.Deep comparison between: Soolantra vs Rhofade with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsRhofade has a higher rate of injection site reactions vs Soolantra based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Rhofade but not Soolantra, including UnitedHealthcare
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Category
Soolantra
Rhofade
At A Glance
Topical
Daily
Macrocyclic lactone
Topical
Daily
Alpha-1A adrenoceptor agonist
Indications
- Rosacea
- Rosacea
Dosing
Rosacea Apply a pea-size amount to each affected area of the face (forehead, chin, nose, each cheek) once daily as a thin layer, avoiding the eyes and lips.
Rosacea Apply a pea-sized amount once daily in a thin layer to cover the entire face (forehead, nose, each cheek, and chin), avoiding the eyes and lips; wash hands immediately after applying.
Contraindications
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—
Adverse Reactions
Most common (<=1%) Skin burning sensation, skin irritation
Postmarketing Contact dermatitis, allergic dermatitis
Most common (>=1%) application site dermatitis, worsening inflammatory lesions of rosacea, application site pruritus, application site erythema, application site pain
Pharmacology
The mechanism of action of Soolantra cream in treating rosacea lesions is unknown; ivermectin is a semi-synthetic macrocyclic lactone derived from Streptomyces avermitilis fermentation belonging to the avermectin family.
Oxymetazoline is an alpha 1A adrenoceptor agonist that acts as a vasoconstrictor when applied topically to the face.
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Most Common Insurance
Anthem BCBS
Soolantra
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (5/12) · Qty limit (9/12)
Rhofade
- Covered on 5 commercial plans
- PA (9/12) · Step Therapy (6/12) · Qty limit (9/12)
UnitedHealthcare
Soolantra
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (4/8)
Rhofade
- Covered on 4 commercial plans
- PA (5/8) · Step Therapy (0/8) · Qty limit (1/8)
Humana
Soolantra
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (3/3) · Qty limit (2/3)
Rhofade
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (2/3) · Qty limit (3/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Soolantra.
No savings programs available for Rhofade.
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SoolantraView full Soolantra profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.