Medications for Paroxysmal Nocturnal Hemoglobinuria

7 results

  • bkemv - eculizumab - aeeb injection, solution, concentrate

    (Eculizumab-Aeeb)
    Amgen Inc
    BKEMV is a complement inhibitor indicated for paroxysmal nocturnal hemoglobinuria (PNH) to reduce hemolysis, atypical hemolytic uremic syndrome (aHUS) to inhibit complement-mediated thrombotic microangiopathy, and generalized myasthenia gravis (gMG) in AChR antibody-positive adults. Not indicated for STEC-HUS.
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    Drug Interactions

  • empaveli - pegcetacoplan injection, solution

    (Pegcetacoplan)
    Apellis Pharmaceuticals, Inc.
    Empaveli is a complement inhibitor for adults with paroxysmal nocturnal hemoglobinuria (PNH), and for adults and patients aged 12 and older with C3 glomerulopathy (C3G) or primary immune-complex membranoproliferative glomerulonephritis (IC-MPGN) to reduce proteinuria.
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  • fabhalta - iptacopan capsule

    (Iptacopan)
    Novartis Pharmaceuticals Corporation
    FABHALTA (complement factor B inhibitor) treats adults with paroxysmal nocturnal hemoglobinuria (PNH), reduces proteinuria in adults with primary IgA nephropathy (IgAN) at risk of rapid disease progression, and treats adults with complement 3 glomerulopathy (C3G) to reduce proteinuria.
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    Drug Interactions

  • soliris - eculizumab injection, solution, concentrate

    (Eculizumab)
    Alexion Pharmaceuticals Inc.
    Soliris treats paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), generalized myasthenia gravis (gMG) in AChR antibody-positive patients aged 6 and older, and neuromyelitis optica spectrum disorder (NMOSD) in AQP4 antibody-positive adults. Not indicated for STEC-HUS.
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    Drug Interactions

  • ultomiris - ravulizumab solution, concentrate

    (Ravulizumab)
    Alexion Pharmaceuticals Inc.
    Ultomiris treats PNH and aHUS (including complement-mediated TMA) in adults and pediatric patients one month and older. Also indicated for AChR antibody-positive generalized myasthenia gravis and AQP4 antibody-positive neuromyelitis optica spectrum disorder in adults. Not for STEC-HUS.
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  • voydeya - danicopan tablet, film coated

    (Danicopan)
    Alexion Pharmaceuticals Inc.
    VOYDEYA is an add-on therapy to ravulizumab or eculizumab for treating extravascular hemolysis (EVH) in adults with paroxysmal nocturnal hemoglobinuria (PNH). Not indicated as monotherapy.
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    Drug Interactions